How to counter Karma
Let us take a look on how to beat Karma. We will look at champions who are strong against Karma and who are weak against Karma. Use win rate, gold difference and creep score difference at minute 10 to find the best 
Support champion who counters Karma. You can already win in champion select with the right counters for Karma. If you want to know how to counter Karma then you need to take into account the best picks vs Karma and the worst picks vs Karma. This Karma counter data is based on matches played by Pros on patch 15.12 and previous ones. It is important to see whether Pros counter picked Karma or whether they played as Karma.
Champions used by Pros to counter pick Karma
Looking at the matches from Pros (see table Pros counter picked Karma) we can see that they picked 
Neeko most often to counter pick Karma. The matchup Neeko vs Karma occured 67 times. Karma has 34 wins and 33 losses in this matchup. Learn how to counter pick Neeko to get another perspective on the data.
Lane outcome for Karma
When looking at Karma counters you will notice that win rates alone are not conclusional. Therefore we provide an overview (see table Lane Outcome) where you can see the lane outcome of Pros who played Karma. The lane outcome of Karma consists of three outcomes: Win, Loss or Draw. Let's take a look of Karma lane and match outcome for specific matchups. Considering the lane outcome and the match outcome of a specific matchup, might enable you to find the right counter for Karma.
Conclusion
Analyze the available data and learn how to beat Karma. To master Karma take also a look on Karma builds and runes for Karma. Good luck, Summoner!